Thursday, March 01, 2007

Medicos Reinventam o Integral!!!!!!!!

Em certos livros de medicina o integral de uma funcao e' chamado de ... AUC = Area Under the Curve.

fico sem palavras. Mas ha' mais... oh sim, se ha' mais.
Na sua santa ignorancia, estes medicos decidiram que afinal era preciso calcular a dita AUC porque "maior" ou "menor" ja nao chega para as exigencias da ciencia de hoje. Entao entra em cena um tal de Tai, que propoe... wait for it... the Tai Method of computing the AUC!!!!! O resto, so' visto:


"A mathematical model for the determination of total area under glucose tolerance and other metabolic curves

MM Tai
Obesity Research Center, St. Luke's-Roosevelt Hospital Center, New York, New York.

OBJECTIVE--To develop a mathematical model for the determination of total areas under curves from various metabolic studies. RESEARCH DESIGN AND METHODS--In Tai's Model, the total area under a curve is computed by dividing the area under the curve between two designated values on the X-axis (abscissas) into small segments (rectangles and triangles) whose areas can be accurately calculated from their respective geometrical formulas. The total sum of these individual areas thus represents the total area under the curve. Validity of the model is established by comparing total areas obtained from this model to these same areas obtained from graphic method (less than +/- 0.4%). Other formulas widely applied by researchers under- or overestimated total area under a metabolic curve by a great margin. RESULTS--Tai's model proves to be able to 1) determine total area under a curve with precision; 2) calculate area with varied shapes that may or may not intercept on one or both X/Y axes; 3) estimate total area under a curve plotted against varied time intervals (abscissas), whereas other formulas only allow the same time interval; and 4) compare total areas of metabolic curves produced by different studies. CONCLUSIONS--The Tai model allows flexibility in experimental conditions, which means, in the case of the glucose-response curve, samples can be taken with differing time intervals and total area under the curve can still be determined with precision. "


Bravo Tai!!! e' ja' um Nobel e uma visita ao tumulo do Leibniz!!!

posted by Pedro at 2:55 PM

2 Comments:

Blogger Peregrino a Meca said...

Mais um caso de descobertas paralelas. O proximo passo sera certamente a invenção de um algoritmo para o calculo da evolução de uma curva.

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